Organoruthenium-catalyzed chemical protein synthesis to elucidate the functions of epigenetic modifications on heterochromatin factors-Reference-Cited by-同舟云学术

Organoruthenium-catalyzed chemical protein synthesis to elucidate the functions of epigenetic modifications on heterochromatin factors

Published:2021 Issue:16 Volume:12 Page:5926-5937
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Kamo Naoki¹²³⁴⁵^ORCID,Kujirai Tomoya⁶⁷³⁸⁵^ORCID,Kurumizaka Hitoshi⁶⁷³⁸⁵^ORCID,Murakami Hiroshi⁹²¹⁰¹¹⁵^ORCID,Hayashi Gosuke⁹²¹⁰¹¹⁵^ORCID,Okamoto Akimitsu¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry and Biotechnology

2. Graduate School of Engineering

3. The University of Tokyo

4. Tokyo 113-8656

5. Japan

6. Laboratory of Chromatin Structure and Function

7. Institute for Quantitative Biosciences

8. Tokyo 113-0032

9. Department of Biomolecular Engineering

10. Nagoya University

11. Nagoya 464-8603

Abstract

Chemical protein synthesis assisted by an organoruthenium catalyst streamlined the production of heterochromatin factors bearing various patterns of epigenetic modifications, and their biological significance was elucidated.

Funder

Japan Society for the Promotion of Science

Japan Agency for Medical Research and Development

Japan Science and Technology Agency

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/SC/D1SC00731A

Reference72 articles.

1. Novel protein science enabled by total chemical synthesis