Development of a capillary electrophoresis system with Mn(ii) complexes and β-cyclodextrin as the dual chiral selectors for enantioseparation of dansyl amino acids and its application in screening enzyme inhibitors
Author:
Affiliation:
1. Beijing National Laboratory for Molecular Sciences
2. Key Laboratory of Analytical Chemistry for Living Biosystems
3. Institute of Chemistry
4. Chinese Academy of Sciences
5. 100190 Beijing
Abstract
A novel CLE-CE system with Mn(ii)–[BMIm][l-Ala] complexes and β-CD as the dual chiral selectors based on the synergistic effect was successfully constructed for enantioseparation of Dns-d,l-AAs and applied in screening the tyrosinase inhibitors.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA02744F
Reference64 articles.
1. Enantioseparation in Capillary Electrophoresis Using 6-Oligo-(lactic acid)cyclomaltoheptaose as a Chiral Selector
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4. Indirect chiral ligand exchange chromatography for enantioseparation: a modification of conventional techniques
5. Development of new chiral ligand exchange capillary electrophoresis system with amino acid ionic liquids ligands and its application in studying the kinetics of l-amino acid oxidase
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