Structural and photodynamic properties of the anti-cancer drug irinotecan in aqueous solutions of different pHs
Author:
Affiliation:
1. Departamento de Química Física
2. Facultad de Ciencias Ambientales y Bioquímica, and INAMOL
3. Universidad de Castilla-La Mancha
4. 45071 Toledo
5. Spain
6. Facultad de Farmacia
7. 02071 Albacete
Abstract
The influence of pH on the structures and dynamics of irinotecan (a potent anti-cancer drug) in water solutions was elucidated.
Funder
Secretaría de Estado de Investigación, Desarrollo e Innovación
Publisher
Royal Society of Chemistry (RSC)
Subject
Physical and Theoretical Chemistry,General Physics and Astronomy
Link
http://pubs.rsc.org/en/content/articlepdf/2018/CP/C8CP01134F
Reference45 articles.
1. Topoisomerase I inhibitors: selectivity and cellular resistance
2. Topoisomerase I inhibitors: camptothecins and beyond
3. Mechanism of action of eukaryotic DNA topoisomerase I and drugs targeted to the enzyme
Cited by 6 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. A dual catalytic functionalized hollow mesoporous silica-based nanocarrier coated with bacteria-derived exopolysaccharides for targeted delivery of irinotecan to colorectal cancer cells;International Journal of Biological Macromolecules;2024-02
2. Preparation of nanosized liquid-like clusters of irinotecan hydrochloride trihydrate for injection concentrate to reduce carbon footprint;International Journal of Pharmaceutics;2023-12
3. DFT studies of camptothecins cytotoxicity IV — active and inactive forms of irinotecan;Acta Chimica Slovaca;2023-01-01
4. Excited-state dynamics of imiquimod in aqueous solutions;Journal of Photochemistry and Photobiology A: Chemistry;2022-10
5. Combination Chemo‐Immunotherapy for Pancreatic Cancer Using the Immunogenic Effects of an Irinotecan Silicasome Nanocarrier Plus Anti‐PD‐1;Advanced Science;2021-01-27
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3