Intratumoral phenotypic heterogeneity as an encourager of cancer invasion-Reference-Cited by-同舟云学术

Intratumoral phenotypic heterogeneity as an encourager of cancer invasion

Published:2014 Issue:7 Volume:6 Page:654-661
ISSN:1757-9694
Container-title:Integr. Biol.
language:en
Short-container-title:Integr. Biol.

Author:

Shin Yoojin¹²³,Han Sewoon¹²³,Chung Euiheon⁴⁵⁶⁷⁵,Chung Seok¹²³

Affiliation:

1. Department of Mechanical Engineering

2. Korea University

3. Seongbuk, South Korea

4. School of Mechatronics

5. Gwangju Institute of Science and Technology

6. Gwangju, South Korea

7. Department of Medical System Engineering

Abstract

We present a novel in vitro breast tumour model to mimic intratumoral phenotypic heterogeneity based on a 3D microfluidic system. With the system, we propose the role of intratumoral heterogeneity in cancer invasion.

Publisher

Oxford University Press (OUP)

Subject

Biochemistry,Biophysics

Link

http://pubs.rsc.org/en/content/articlepdf/2014/IB/C4IB00022F

Reference26 articles.

1. Intra-tumour heterogeneity: a looking glass for cancer?

2. Tumor Heterogeneity: Mechanisms and Bases for a Reliable Application of Molecular Marker Design

3. The tumor microenvironment: regulation by MMP-independent effects of tissue inhibitor of metalloproteinases-2

4. Tumor microenvironment and progression

5. Intratumor Heterogeneity: Seeing the Wood for the Trees

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