The detrimental invasiveness of glioma cells controlled by gadolinium chelate-coated gold nanoparticles

Author:

Durand Maxime12345,Lelievre Elodie67895,Chateau Alicia12345,Berquand Alexandre61095,Laurent Gautier111213145,Carl Philippe15165,Roux Stéphane111213145,Chazee Lise67895,Bazzi Rana111213145,Eghiaian Frederic17185,Jubreaux Justine12345,Ronde Philippe15165,Barberi-Heyob Muriel12345,Chastagner Pascal12345,Devy Jérôme67895,Pinel Sophie12345ORCID

Affiliation:

1. Université de Lorraine

2. CNRS

3. CRAN

4. F-54000 Nancy

5. France

6. Université de Reims-Champagne-Ardennes

7. UMR CNRS/URCA 7369

8. MEDyC

9. F-51100 Reims

10. EA 4682

11. Université Bourgogne Franche-Comté

12. UMR CNRS 6213-UBFC

13. UTINAM

14. F-25000 Besançon

15. Université de Strasbourg

16. CNRS UMR 7021 – Strasbourg

17. Abberior Instruments GmbH

18. F-13008 Marseille

Abstract

The invasive phenotype of glioma cells is thought to be responsible for recurrences. Ultrasmall Gd3+ chelate-coated gold nanoparticles interfere with cells capacities to migrate and invade due to induced changes in intrinsic biomechanical properties.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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