Continuous cell sorting in a flow based on single cell resonance Raman spectra-Reference-Cited by-同舟云学术

Continuous cell sorting in a flow based on single cell resonance Raman spectra

Published:2016 Issue:8 Volume:16 Page:1420-1429
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

McIlvenna David¹²³⁴⁵,Huang Wei E.⁶⁷⁸⁵,Davison Paul⁹¹⁰¹¹¹²¹³,Glidle Andrew¹²³⁴⁵,Cooper Jon¹²³⁴⁵,Yin Huabing¹²³⁴⁵

Affiliation:

1. Division of Biomedical Engineering

2. School of Engineering

3. University of Glasgow

4. Glasgow

5. UK

6. Department of Engineering Science

7. University of Oxford

8. Oxford OX1 3PJ

9. Kroto Research Institute

10. Department of Civil and Structural Engineering

11. North Campus

12. The University of Sheffield

13. Sheffield S3 7HQ

Abstract

A chip-based Raman activated cell sorting system is developed, which demonstrates continuous and automated sorting of individual cells in a flow, based on their intrinsic resonance Raman spectra. This platform allows the isolation of cells in their native fluid with the ability to achieve high accuracy sorting of 96.3%.

Funder

Engineering and Physical Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2016/LC/C6LC00251J

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1. Tumour evolution inferred by single-cell sequencing

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