A novel sulfamethazine-based pH-sensitive copolymer for injectable radiopaque embolic hydrogels with potential application in hepatocellular carcinoma therapy-Reference-Cited by-同舟云学术

A novel sulfamethazine-based pH-sensitive copolymer for injectable radiopaque embolic hydrogels with potential application in hepatocellular carcinoma therapy

Published:2016 Issue:37 Volume:7 Page:5805-5818
ISSN:1759-9954
Container-title:Polymer Chemistry
language:en
Short-container-title:Polym. Chem.

Author:

Nguyen Quang Vinh¹²³⁴,Lym Jae Seung¹²³⁴,Huynh Cong Truc¹²³⁴⁵^ORCID,Kim Bong Sup¹²³⁴,Jae Hwan Jun⁶⁷⁸⁴,Kim Young Il⁶⁷⁸⁴⁶,Lee Doo Sung¹²³⁴

Affiliation:

1. Theranostic Macromolecules Research Center and School of Chemical Engineering

2. Sungkyunkwan University

3. Suwon

4. Korea

5. Department of Biomedical Engineering

6. Department of Radiology

7. Seoul National University Hospital

8. Seoul

Abstract

After transcatheter delivery through hepatic artery, a hydrogel can be formed within tumor vasculature by the decrease of environmental pH, block the blood vessel and control the release of loaded anticancer drugs.

Funder

National Research Foundation of Korea

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2016/PY/C6PY01141A

Reference57 articles.

1. Diagnosis, staging and treatment of hepatocellular carcinoma

2. Hepatocellular Carcinoma: Epidemiology and Molecular Carcinogenesis

3. Epidemiology of Hepatocellular Carcinoma