Dual-biomarker-triggered fluorescence probes for differentiating cancer cells and revealing synergistic antioxidant effects under oxidative stress

Author:

Zhang Changyu1234,Zhang Qiang-Zhe56784,Zhang Kun56784,Li Lu-Yuan56784,Pluth Michael D.910111213ORCID,Yi Long1234ORCID,Xi Zhen141516177

Affiliation:

1. State Key Laboratory of Organic-Inorganic Composites

2. Beijing University of Chemical Technology (BUCT)

3. Beijing 100029

4. China

5. State Key Laboratory of Medicinal Chemical Biology

6. College of Pharmacy

7. Nankai University

8. Tianjin 300071

9. Materials Science Institute

10. Institute of Molecular Biology

11. Department of Chemistry and Biochemistry

12. University of Oregon

13. Eugene

14. State Key Laboratory of Elemento-Organic Chemistry

15. College of Chemistry

16. National Pesticide Engineering Research Center (Tianjin)

17. Collaborative Innovation Center of Chemical Science and Engineering

Abstract

Dual-biomarker-triggered fluorescent probes were developed for simultaneous detection of the two biomarkers H2S and hNQO1 in cancer cells.

Funder

National Natural Science Foundation of China

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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