The role of metals in mammalian olfaction of low molecular weight organosulfur compounds

Author:

Block Eric12345ORCID,Batista Victor S.1675ORCID,Matsunami Hiroaki89101112ORCID,Zhuang Hanyi1314151617ORCID,Ahmed Lucky1675ORCID

Affiliation:

1. Department of Chemistry

2. University at Albany

3. State University of New York

4. Albany

5. USA

6. Yale University

7. New Haven

8. Department of Molecular Genetics and Microbiology

9. Department of Neurobiology

10. Duke Institute for Brain Sciences

11. Duke University Medical Center

12. Durham

13. Institutes of Health Sciences

14. Shanghai Jiaotong University School of Medicine

15. Shanghai Institutes for Biological Science of Chinese Academy of Sciences

16. Shanghai 200031

17. China

Abstract

We highlight the role that copper and other metals play in mammalian olfaction of low molecular weight organosulfur compounds from both natural and non-natural sources.

Funder

National Science Foundation

Science and Technology Commission of Shanghai Municipality

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference239 articles.

1. X. Su , H.Matsunami and H.Zhuang, in Bioelectronic Nose, ed. T. H. Park, Springer, 2014, ch. 4, pp. 69–81

2. G. Ohloff , W.Pickenhagen and P.Kraft, Scent and Chemistry: The Molecular World of Odors, Wiley-VCH, Zurich, 2012

3. Chemical constituents of the defensive secretion of the striped skunk (Mephitis mephitis)

4. Exudation of low molecular weight compounds (thiobismethane, methyl isocyanide, and methyl isothiocyanate) as a possible chemical defense mechanism in the marine sponge Ircinia felix

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