Imaging acetaldehyde formation during ethanol metabolism in living cells using a hydrazinyl naphthalimide fluorescent probe
Author:
Affiliation:
1. Department of Chemistry
2. Southern Methodist University
3. Dallas
4. USA
5. Center for Drug Discovery, Design, and Delivery (CD4)
Abstract
The metabolism of ethanol to acetaldehyde has been visualized in living lung epithelial cells using a hydrazinyl naphthalimide fluorescent probe.
Funder
National Institute of General Medical Sciences
Publisher
Royal Society of Chemistry (RSC)
Subject
General Engineering,General Chemical Engineering,Analytical Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/AY/C7AY01238A
Reference29 articles.
1. The Role of Acetaldehyde in the Actions of Alcohol (Update 2000)
2. Alcohol and airways function in health and disease
3. Genetic polymorphism and activities of human lung alcohol and aldehyde dehydrogenases: Implications for ethanol metabolism and cytotoxicity
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