Diblock copolymer glyco-nanomicelles constructed by a maltoheptaose-based amphiphile for reduction- and pH-mediated intracellular drug delivery

Author:

Cheng Lulu12345,Luan Tingting12345,Liu Di6457,Cheng Ju6457,Li Hongping12345,Wei Hua12345ORCID,Zhang Lifen12345,Lan Jingfeng12345,Liu Yali897,Zhao Guanghui12345ORCID

Affiliation:

1. State Key Laboratory of Applied Organic Chemistry

2. Institute of Biochemical Engineering & Environmental Technology

3. College of Chemistry and Chemical Engineering

4. Lanzhou University

5. Lanzhou 730000

6. School of Basic Medical Sciences

7. People's Republic of China

8. Gansu Provincial Maternity and Child-care Hospital

9. Lanzhou 730050

Abstract

A new type of reduction- and pH-mediated glyco-polymeric micelles was synthesized for the antitumor drug doxorubicin (DOX) delivery in this study.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Gansu Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering

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