Effect of molar mass and alkyl chain length on the surface properties and biocompatibility of poly(alkylene terephthalate)s for potential cardiovascular applications

Author:

Van Daele Lenny1ORCID,Van de Voorde Babs1ORCID,Colenbier Robin12ORCID,De Vos Lobke1ORCID,Parmentier Laurens1ORCID,Van der Meeren Louis3ORCID,Skirtach André3ORCID,Dmitriev Ruslan I.2ORCID,Dubruel Peter1ORCID,Van Vlierberghe Sandra1ORCID

Affiliation:

1. Polymer Chemistry and Biomaterials Group (PBM), Centre of Macromolecular Chemistry (CMaC), Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281 S4, 9000 Ghent, Belgium

2. Tissue engineering and Biomaterials Group, Department of Human structure and repair, Faculty of Medicine and Health Sciences, Ghent University, C. Heymanslaan 10, 6B3, UZP123, 9000 Ghent, Belgium

3. Department of Biotechnology, Ghent University, Proeftuinstraat 86, 9000 Ghent, Belgium

Abstract

A series of poly(alkylene terephthalate)s was synthesized and the effect of the polymer molar mass and alkyl chain length on the surface properties of spin-coated films was investigated, as well as the endothelial cell adhesion and proliferation.

Funder

Agentschap Innoveren en Ondernemen

Fonds Wetenschappelijk Onderzoek

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Reference72 articles.

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2. WHO, Cardiovascular diseases (CVDs), https://www.who.int/en/news-room/fact-sheets/detail/cardiovascular-diseases-(cvds)

3. The Pathogenesis of Coronary Artery Disease and the Acute Coronary Syndromes

4. 2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes

5. 2021 ESC Guidelines on cardiovascular disease prevention in clinical practice

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