Nanofocused synchrotron X-ray absorption studies of the intracellular redox state of an organometallic complex in cancer cells-Reference-Cited by-同舟云学术

Nanofocused synchrotron X-ray absorption studies of the intracellular redox state of an organometallic complex in cancer cells

Published:2019 Issue:49 Volume:55 Page:7065-7068
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Sanchez-Cano Carlos¹²³⁴^ORCID,Gianolio Diego⁵⁶⁷⁴,Romero-Canelon Isolda¹²³⁴^ORCID,Tucoulou Remi⁸⁹¹⁰¹¹,Sadler Peter J.¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. University of Warwick

3. Coventry

4. UK

5. Diamond Light Source

6. Harwell Science and Innovation Campus

7. Didcot

8. ESRF

9. The European Synchrotron

10. Grenoble

11. France

Abstract

Synchrotron nanoprobe X-ray absorption studies of an osmium metallodrug in cancer cells show hetereogeneous intracellular distribution of Os^II and Os^III species.

Funder

Engineering and Physical Sciences Research Council

Cancer Research UK

Wellcome Trust

European Synchrotron Radiation Facility

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2019/CC/C9CC01675A

Reference48 articles.

1. Application of Metal Coordination Chemistry To Explore and Manipulate Cell Biology

2. Bioorganometallics: Future Trends in Drug Discovery, Analytical Chemistry, and Catalysis,

3. D. Rehder and E.Nordlander , Bioinorganic Chemistry: An Introduction , 2014

4. Designed transition metal catalysts for intracellular organic synthesis

5. Anticancer Activity of Metal Complexes: Involvement of Redox Processes

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