Diagnosis of penicillin allergy: a MOFs-based composite hydrogel for detecting β-lactamase in serum

Author:

Lian Xiao12345,Yan Bing12345ORCID

Affiliation:

1. Shanghai Key Lab of Chemical Assessment and Sustainability

2. School of Chemical Science and Engineering

3. Tongji University

4. Shanghai 200092

5. China

Abstract

A MOFs-based composite hydrogel 1@SA is presented for the diagnosis of penicillin anaphylaxis. This composite hydrogel reflects the enzymatic hydrolysis profiles of penicillin via β-lactamase. The determination of β-lactamase by this hydrogel was achieved through an “ON–OFF–OFF–ON” fluorescence trigger pattern. The potency of 1@SA was further demonstrated for its selectivity, sensitivity and convenient visual detection.

Funder

National Natural Science Foundation of China

Tongji University

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3