Synthesis of dihydroisoindolo[2,1-a]quinolin-11-ones, their in silico ADMET properties and in vitro antitumor activities-Reference-Cited by-同舟云学术

Synthesis of dihydroisoindolo[2,1-a]quinolin-11-ones, their in silico ADMET properties and in vitro antitumor activities

Published:2020 Issue:69 Volume:10 Page:42287-42296
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Merchán-Arenas Diego R.¹²³⁴⁵^ORCID,Sojo Felipe⁶⁷⁸⁹¹⁰,Arvelo Francisco⁶⁷⁸⁹¹⁰,Kouznetsov Vladimir V.¹²³⁴⁵^ORCID

Affiliation:

1. Laboratorio de Química Orgánica y Biomolecular

2. Universidad Industrial de Santander

3. Parque Tecnológico Guatiguará

4. Piedecuesta

5. Colombia

6. Centro de Biociencias

7. Fundación Instituto de Estudios Avanzados-IDEA

8. Caracas

9. Venezuela

10. Laboratorio de Cultivo de Tejidos y Biología de Tumores

Abstract

We synthesized a series of dihydroisoindolo[2,1-a]quinolin-11-ones using the imino Diels–Alder reaction and evaluated their biological properties, finding a new hit in anticancer research.

Funder

Departamento Administrativo de Ciencia, Tecnología e Innovación

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/RA/D0RA04555A

Reference48 articles.

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