Targeted CT/MR dual mode imaging of human hepatocellular carcinoma using lactobionic acid-modified polyethyleneimine-entrapped gold nanoparticles

Author:

Li Du1234,Yang Jia56789,Wen Shihui1011234,Shen Mingwu1011234,Zheng Linfeng56789,Zhang Guixiang56789,Shi Xiangyang123410ORCID

Affiliation:

1. State Key Laboratory for Modification of Chemical Fibers and Polymer Materials & College of Materials Science and Engineering

2. Donghua University

3. Shanghai 201620

4. People's Republic of China

5. Department of Radiology

6. Shanghai General Hospital

7. School of Medicine

8. Shanghai Jiaotong University

9. Shanghai 200080

10. College of Chemistry

11. Chemical Engineering and Biotechnology

Abstract

Multifunctional PEI-entrapped gold nanoparticles modified with lactobionic acid enable efficient targeted dual mode CT/MR imaging of human hepatocellular carcinoma.

Funder

Science and Technology Commission of Shanghai Municipality

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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