Biosynthesis of the fungal glyceraldehyde-3-phosphate dehydrogenase inhibitor heptelidic acid and mechanism of self-resistance-Reference-Cited by-同舟云学术

Biosynthesis of the fungal glyceraldehyde-3-phosphate dehydrogenase inhibitor heptelidic acid and mechanism of self-resistance

Author:

Yan Yan¹²³^ORCID,Zang Xin⁴⁵⁶⁷⁸,Jamieson Cooper S.⁹²³^ORCID,Lin Hsiao-Ching¹²³^ORCID,Houk K. N.⁹²³^ORCID,Zhou Jiahai⁴⁵⁶⁷⁸,Tang Yi¹²³⁹²^ORCID

Affiliation:

1. Department of Chemical and Biomolecular Engineering

2. University of California Los Angeles

3. USA

4. State Key Laboratory of Bio-organic and Natural Products Chemistry

5. Center for Excellence in Molecular Synthesis

6. Shanghai Institute of Organic Chemistry

7. University of Chinese Academy of Sciences

8. Shanghai 200032

9. Department of Chemistry and Biochemistry

Abstract

The structural basis and self-resistance mechanism of fungal glyceraldehyde-3-phosphate dehydrogenase inhibitor heptelidic acid are uncovered.

Funder

National Institutes of Health

Ministry of Science and Technology of the People's Republic of China

Chinese Academy of Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

Reference50 articles.

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