Chemoenzymatic synthesis of heparan sulfate and heparin
Author:
Affiliation:
1. Division of Chemical Biology and Medicinal Chemistry
2. Eshelman School of Pharmacy
3. University of North Carolina
4. Chapel Hill, USA
5. Department of Chemistry and Chemical Biology
6. Rensselaer Polytechnic Institute
7. Troy, USA
Abstract
Heparin and heparan sulfate are sulfated carbohydrates that display a wide range of biological functions. A chemoenzymatic method is becoming a promising approach to synthesize heparin-like oligosaccharides with high efficiency.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2014/NP/C4NP00076E
Reference57 articles.
1. Heparan sulphate proteoglycans fine-tune mammalian physiology
2. Prevention of VTE in Nonsurgical Patients
3. 2003 Claude S. Hudson Award Address in Carbohydrate Chemistry. Heparin: Structure and Activity
4. Modular Synthesis of Heparan Sulfate Oligosaccharides for Structure−Activity Relationship Studies
5. Synthesis of 3-O-sulfonated heparan sulfate octasaccharides that inhibit the herpes simplex virus type 1 host–cell interaction
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