Isolation and biosynthesis of labdanmycins: four new labdane diterpenes from endophyticStreptomyces
Author:
Affiliation:
1. State Key Laboratory of Phytochemistry and Plant Resources in West China
2. CAS Center for Excellence in Molecular Plant Sciences
3. Kunming Institute of Botany
4. Chinese Academy of Sciences
5. Kunming 650204
Abstract
The gene cluster of two new labdanmycins was identified from an endophyticStreptomyces. The P450 enzyme LabE was confirmed to oxidize C-20 methyl of the biosynthetic intermediate3to afford labdanmycins.
Funder
National Natural Science Foundation of China
Applied Basic Research Foundation of Yunnan Province
Chinese Academy of Sciences
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/QO/C8QO00085A
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