Cationic polymer synergizing with chemotherapeutics and re-purposing antibiotics against cancer cells-Reference-Cited by-同舟云学术

Cationic polymer synergizing with chemotherapeutics and re-purposing antibiotics against cancer cells

Published:2021 Issue:6 Volume:9 Page:2174-2182
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Zheng Yiran¹²³⁴⁵,Kng Jessica⁵⁶⁷⁸,Yang Chuan⁵⁶⁷⁸^ORCID,Hedrick James L.⁹¹⁰¹¹,Yang Yi Yan⁵⁶⁷⁸^ORCID

Affiliation:

1. College of Pharmaceutical Sciences

2. Soochow University

3. Suzhou 215123

4. P. R. China

5. Institute of Bioengineering and Nanotechnolgy

6. Agency for Science Technology and Research. 31 Biopolis way

7. Singapore 138669

8. Singapore

9. IBM Almaden Research Center

10. San Jose

11. USA

Abstract

A quaternary ammonium-functionalized cationic polymer synergizes with existing chemotherapeutics and re-purposes antibiotics to increase therapeutic efficacy, mitigate toxicity and circumvent drug resistance via its membrane disruption mechanism.

Funder

Agency for Science, Technology and Research

National Medical Research Council

International Business Machines Corporation

Natural Science Foundation of Jiangsu Province

Suzhou Municipal Science and Technology Bureau

Priority Academic Program Development of Jiangsu Higher Education Institutions

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/BM/D0BM02155E

Reference50 articles.

1. Chemotherapy and the war on cancer

2. Advanced targeted therapies in cancer: Drug nanocarriers, the future of chemotherapy

3. Phase III Trial of Doxorubicin, Paclitaxel, and the Combination of Doxorubicin and Paclitaxel as Front-Line Chemotherapy for Metastatic Breast Cancer: An Intergroup Trial (E1193)

4. Breast Cancer Treatment

5. Dual HER2 Targeting with Trastuzumab and Liposomal-Encapsulated Doxorubicin (MM-302) Demonstrates Synergistic Antitumor Activity in Breast and Gastric Cancer

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