A <i>Lupinus angustifolius</i> protein hydrolysate exerts hypocholesterolemic effects in Western diet-fed ApoE<sup>−/−</sup> mice through the modulation of LDLR and PCSK9 pathways-Reference-Cited by-同舟云学术

A Lupinus angustifolius protein hydrolysate exerts hypocholesterolemic effects in Western diet-fed ApoE^−/− mice through the modulation of LDLR and PCSK9 pathways

Published:2022 Issue:7 Volume:13 Page:4158-4170
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Santos-Sánchez Guillermo¹²³^ORCID,Cruz-Chamorro Ivan¹²³^ORCID,Bollati Carlotta¹^ORCID,Bartolomei Martina¹^ORCID,Pedroche Justo⁴,Millán Francisco⁴,Millán-Linares María del Carmen²⁴^ORCID,Capriotti Anna Laura⁵^ORCID,Cerrato Andrea⁵^ORCID,Laganà Aldo⁵^ORCID,Arnoldi Anna¹,Carrillo-Vico Antonio²³^ORCID,Lammi Carmen¹^ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, University of Milan, 20133 Milan, Italy

2. Departamento de Bioquímica Médica y Biología Molecular e Inmunología, Universidad de Sevilla, 41009 Seville, Spain

3. Instituto de Biomedicina de Sevilla, IBiS (Universidad de Sevilla, HUVR, Junta de Andalucía, CSIC), 41013 Seville, Spain

4. Department of Food & Health, Instituto de la Grasa, CSIC, Ctra, Utrera Km 1, 41013 Seville, Spain

5. Dipartimento di Chimica, Sapienza Università di Roma, Piazzale Aldo Moro 5, 00185 Rome, Italy

Abstract

Lupin protein hydrolysates (LPHs) are gaining attention in the food and nutraceutical industries due to their several beneficial health effects.

Funder

Universidad de Sevilla

Consejería de Economía, Conocimiento, Empresas y Universidad, Junta de Andalucía

Ministerio de Educación, Cultura y Deporte

Erasmus+

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/FO/D1FO03847H

Reference67 articles.

1. The health benefits of sweet lupin seed flours and isolated proteins

2. GPETAFLR, a novel bioactive peptide from Lupinus angustifolius L. protein hydrolysate, reduces osteoclastogenesis

3. GPETAFLR, a biopeptide from Lupinus angustifolius L., protects against oxidative and inflammatory damage in retinal pigment epithelium cells

4. A multidisciplinary investigation on the bioavailability and activity of peptides from lupin protein

5. Trans-Epithelial Transport, Metabolism, and Biological Activity Assessment of the Multi-Target Lupin Peptide LILPKHSDAD (P5) and Its Metabolite LPKHSDAD (P5-Met)

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