Hepatoprotective efficacy and interventional mechanism of the panaxadiol saponin component in high-fat diet-induced NAFLD mice-Reference-Cited by-同舟云学术

Hepatoprotective efficacy and interventional mechanism of the panaxadiol saponin component in high-fat diet-induced NAFLD mice

Published:2024 Issue:2 Volume:15 Page:794-808
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Mi Ai¹²^ORCID,Hu Qinxue¹²,Liu Ying¹²,Zhao Yanna¹²,Shen Fenglin¹²,Lan Jinjian¹²,Lv Keren¹²,Wang Bolin¹²,Gao Ruilan¹²,Yu Xiaoling¹²

Affiliation:

1. Institute of Hematology Research, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China

2. Zhejiang Provincial Hospital of Traditional Chinese Medicine, Hangzhou, Zhejiang, China

Abstract

PDS-C attenuates NAFLD symptoms and exerts hepatoprotective effects by regulating the AMPK/Nrf2/NFκB signaling axis in vivo and in vitro. In NAFLD, PDS-C has a similar effect to metformin and has good application prospects.

Funder

State Administration of Traditional Chinese Medicine of the People's Republic of China

Ministry of Science and Technology of the People's Republic of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2024/FO/D3FO03572G

Reference88 articles.

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