Potential and performance of anisotropic <sup>19</sup>F NMR for the enantiomeric analysis of fluorinated chiral active pharmaceutical ingredients-Reference-Cited by-同舟云学术

Potential and performance of anisotropic ¹⁹F NMR for the enantiomeric analysis of fluorinated chiral active pharmaceutical ingredients

Published:2024 Issue:11 Volume:149 Page:3204-3213
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Gouilleux Boris¹^ORCID,Moussallieh François-Marie¹^ORCID,Lesot Philippe¹²^ORCID

Affiliation:

1. Université Paris-Saclay, UFR d'Orsay, RMN en Milieu Orienté, ICMMO, UMR CNRS 8182, Bât. HM1, 17-19, Avenue des Sciences, 91400, Orsay, France

2. Centre National de la Recherche Scientifique (CNRS), 3, Rue Michel Ange, F-75016 Paris, France

Abstract

A new analytical strategy involving 1H–{19F} 1D NMR in PBLG-based anisotropic media is explored to analyze fluorinated chiral active pharmaceutical ingredients.

Funder

Université Paris-Saclay

Centre National de la Recherche Scientifique

Agence Nationale de la Recherche

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/AN/D4AN00237G

Reference45 articles.

1. Chiral pharmaceuticals: A review on their environmental occurrence and fate processes

2. The Significance of Chirality in Drug Design and Development

3. The market of chiral drugs: Chiral switches versus de novo enantiomerically pure compounds

4. Chiral discrimination and enantioselective analysis of drugs: An overview

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