Personalized protein corona on nanoparticles and its clinical implications
Author:
Affiliation:
1. Center for Nanomedicine and Department of Anesthesiology
2. Brigham and Women's Hospital
3. Harvard Medical School
4. Boston
5. USA
6. Center for Biomimetic Medicine
7. Houston Methodist Research Institute
8. Houston
Abstract
It is increasingly being accepted that the protein corona is strongly affected by the patient's specific disease. Therefore, the same nanomaterial incubated with plasma proteins of patients with different pathologies adsorb protein coronas with different compositions, giving rise to the concept of personalized protein corona.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering
Link
http://pubs.rsc.org/en/content/articlepdf/2017/BM/C6BM00921B
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