Mitochondrial selectivity and remarkable photocytotoxicity of a ferrocenyl neodymium(iii) complex of terpyridine and curcumin in cancer cells

Author:

Sarkar Tukki1234,Banerjee Samya5674,Mukherjee Sanjoy5674,Hussain Akhtar1234

Affiliation:

1. Department of Chemistry

2. Handique Girls’ College

3. Guwahati 781001

4. India

5. Department of Inorganic and Physical Chemistry

6. Indian Institute of Science

7. Bangalore 560 012

Abstract

A mixed-ligand neodymium(iii) complex of ferrocene appended terpyridine and curcumin targets the mitochondria and shows remarkable visible-light induced cytotoxicity in HeLa and MCF-7 cancer cells while being much less toxic in dark and to MCF-10A normal cells.

Funder

Department of Biotechnology , Ministry of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

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