Mitochondrial selectivity and remarkable photocytotoxicity of a ferrocenyl neodymium(iii) complex of terpyridine and curcumin in cancer cells
Author:
Affiliation:
1. Department of Chemistry
2. Handique Girls’ College
3. Guwahati 781001
4. India
5. Department of Inorganic and Physical Chemistry
6. Indian Institute of Science
7. Bangalore 560 012
Abstract
A mixed-ligand neodymium(iii) complex of ferrocene appended terpyridine and curcumin targets the mitochondria and shows remarkable visible-light induced cytotoxicity in HeLa and MCF-7 cancer cells while being much less toxic in dark and to MCF-10A normal cells.
Funder
Department of Biotechnology , Ministry of Science and Technology
Publisher
Royal Society of Chemistry (RSC)
Subject
Inorganic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/DT/C5DT04775G
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