Small angle X-ray scattering analysis of Cu2+-induced oligomers of the Alzheimer's amyloid β peptide-Reference-Cited by-同舟云学术

Small angle X-ray scattering analysis of Cu2+-induced oligomers of the Alzheimer's amyloid β peptide

Published:2015 Issue:3 Volume:7 Page:536-543
ISSN:1756-5901
Container-title:Metallomics
language:en
Short-container-title:Metallomics

Author:

Ryan Timothy M.¹²³,Kirby Nigel⁴⁵⁶,Mertens Haydyn D. T.⁴⁵⁶,Roberts Blaine¹²³,Barnham Kevin J.¹²³⁷⁸,Cappai Roberto⁷⁸⁹¹⁰,Pham Chi Le Lan⁷⁸⁹¹⁰,Masters Colin L.¹²³,Curtain Cyril C.¹²³⁷⁸

Affiliation:

1. University of Melbourne

2. Florey Institute of Neuroscience and Mental Health

3. Victoria 3010, Australia

4. SAXS/WAXS Beamline

5. The Australian Synchrotron

6. Clayton, Australia

7. Department of Pathology

8. Bio21 Molecular Science and Technology Institute

9. The University of Melbourne

10. Victoria, Australia

Abstract

Research into causes of Alzheimer's disease and its treatment has produced a tantalising array of hypotheses about the role of transition metal dyshomeostasis, many of them on the interaction of these metals with the neurotoxic amyloid-β peptide (Aβ).

Funder

National Health and Medical Research Council

Alzheimer's Australia

Publisher

Oxford University Press (OUP)

Subject

Metals and Alloys,Biochemistry,Biomaterials,Biophysics,Chemistry (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2015/MT/C4MT00323C

Reference53 articles.

1. Cognitive consequences of high Aβ amyloid in mild cognitive impairment and healthy older adults: Implications for early detection of Alzheimer’s disease.

2. Soluble Aβ oligomer production and toxicity