Probing the origin of estrogen receptor alpha inhibition via large-scale QSAR study

Author:

Suvannang Naravut12345ORCID,Preeyanon Likit62345ORCID,Malik Aijaz Ahmad12345ORCID,Schaduangrat Nalini12345ORCID,Shoombuatong Watshara12345ORCID,Worachartcheewan Apilak62345ORCID,Tantimongcolwat Tanawut72345ORCID,Nantasenamat Chanin12345ORCID

Affiliation:

1. Center of Data Mining and Biomedical Informatics

2. Faculty of Medical Technology

3. Mahidol University

4. Bangkok 10700

5. Thailand

6. Department of Community Medical Technology

7. Center for Research and Innovation

Abstract

This study compiles a large, non-redundant set of compounds tested for ERα inhibitory activity and applies QSAR modeling for unveiling the privileged substructures governing the activity.

Funder

Vetenskapsrådet

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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