Cell internalization kinetics and surface charge accessibility of surface-modified PAMAM dendrimers-Reference-Cited by-同舟云学术

Cell internalization kinetics and surface charge accessibility of surface-modified PAMAM dendrimers

Published:2023 Issue:38 Volume:21 Page:7782-7790
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Díaz Carola F.¹,Cifuentes Diego L.²^ORCID,Oyarzún Maximiliano²,Jiménez Verónica A.¹^ORCID,Guzmán Leonardo²

Affiliation:

1. Departamento de Ciencias Químicas, Facultad de Ciencias Exactas, Universidad Andres Bello, Autopista Concepción-Talcahuano 7100, Talcahuano, Chile

2. Departamento de Fisiología, Facultad de Ciencias Biológicas, Universidad de Concepción, Barrio Universitario S/N, Concepción, Chile

Abstract

The accessibility of surface cationic charges is a key determinant for the cell internalization capacity of surface-modified PAMAM dendrimers with acetyl, folate or poly(ethylene glycol) groups.

Funder

Universidad de Concepción

Fondo Nacional de Desarrollo Científico y Tecnológico

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D3OB01265D

Reference48 articles.

1. Dendrimers: Advancements and Potential Applications in Cancer Diagnosis and Treatment—An Overview

2. A review on synthesis and applications of dendrimers

3. Poly(amidoamine) (PAMAM) dendrimers: from biomimicry to drug delivery and biomedical applications

4. Hybrid Nanoparticle System Integrating Tumor-Derived Exosomes and Poly(amidoamine) Dendrimers: Implications for an Effective Gene Delivery Platform

5. Overcoming barriers in non-viral gene delivery for neurological applications

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