A simple and sensitive detection of small molecule–protein interactions based on terminal protection-mediated exponential strand displacement amplification

Author:

Lee Chang Yeol1234,Kim Hyo Yong1234,Kim Soeun1234,Park Ki Soo56784ORCID,Park Hyun Gyu1234ORCID

Affiliation:

1. Department of Chemical and Biomolecular Engineering (BK 21 + program)

2. KAIST

3. Daejeon 34141

4. Republic of Korea

5. Department of Biological Engineering

6. College of Engineering

7. Konkuk University

8. Seoul 05029

Abstract

A new strategy to detect a small molecule–protein interaction was devised based on terminal protection-mediated exponential strand displacement amplification (eSDA).

Funder

Ministry of Science, ICT and Future Planning

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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