Scar tissue removal-activated endogenous neural stem cells aid Taxol-modified collagen scaffolds in repairing chronic long-distance transected spinal cord injury-Reference-Cited by-同舟云学术

Scar tissue removal-activated endogenous neural stem cells aid Taxol-modified collagen scaffolds in repairing chronic long-distance transected spinal cord injury

Published:2021 Issue:13 Volume:9 Page:4778-4792
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Yin Wen¹²³⁴⁵,Xue Weiwei⁶⁷⁸⁹⁵,Zhu Hecheng¹⁰⁴⁵,Shen He¹¹¹²¹³⁸¹⁴,Xiao Zhifeng⁶⁷⁸⁹⁵,Wu Shuyu¹²³⁴⁵,Zhao Yannan⁶⁷⁸⁹⁵,Cao Yudong¹²³⁴⁵,Tan Jun¹²³⁴⁵,Li Juan¹²³⁴⁵,Liu Weidong¹⁵¹⁶¹⁷¹⁸⁴,Wang Lei¹⁵¹⁶¹⁷¹⁸⁴,Meng Li¹⁹²³⁴⁵,Chen Bing⁶⁷⁸⁹⁵,Zhao Ming¹⁰⁴⁵,Jiang Xingjun¹²³⁴⁵,Li Xing⁶⁷⁸⁹⁵^ORCID,Ren Caiping¹⁵¹⁶¹⁷¹⁸⁴,Dai Jianwu⁶⁷⁸⁹⁵^ORCID

Affiliation:

1. Department of Neurosurgery

2. Xiangya Hospital

3. Central South University (CSU)

4. Changsha

5. China

6. State Key Laboratory of Molecular Developmental Biology

7. Institute of Genetics and Developmental Biology

8. Chinese Academy of Sciences

9. Beijing

10. Changsha Kexin Cancer Hospital

11. Key Laboratory for Nano-Bio Interface Research

12. Division of Nanobiomedicine

13. Suzhou Institute of Nano-Tech and Nano-Bionics

14. Suzhou 215123

15. Cancer Research Institute

16. Key Laboratory for Carcinogenesis of Chinese Ministry of Health

17. School of Basic Medical Science

18. Central South University

19. Department of Radiology

Abstract

Only the first scar tissue removal is a key time point for chronic complete SCI repair. Endogenous NSCs could be intensively activated after the first scar tissue removal and contribute to the chronic SCI repair after bio-scaffold implantation.

Funder

National Natural Science Foundation of China

Chinese Academy of Sciences

National Key Research and Development Program of China

Jiangsu Provincial Key Research and Development Program

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/BM/D1BM00449B

Reference62 articles.