N-Heterocyclic carbene-catalyzed radical ring-opening acylation of oxime esters with aldehydes-Reference-Cited by-同舟云学术

N-Heterocyclic carbene-catalyzed radical ring-opening acylation of oxime esters with aldehydes

Published:2021 Issue:21 Volume:8 Page:6074-6079
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Zhang Zhihao¹,Zou Xin¹,Li Zhenjiang¹²^ORCID,Gao Yu¹,Qu Yuanyuan¹,Quan Yusheng¹,Zhou Yi¹,Li Jinlan¹,Sun Jie³^ORCID,Guo Kai¹²^ORCID

Affiliation:

1. College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, 30 Puzhu Road South, Nanjing 211816, P. R. China

2. State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Tech University, 30 Puzhu Road South, Nanjing 211816, P. R. China

3. College of Food Science and Light Industry, Nanjing Tech University, 30 Puzhu Road South, Nanjing 211816, P. R. China

Abstract

We report a radical cross-coupling of cycloketone oxime esters with aldehydes by N-heterocyclic carbene (NHC) organocatalysis. This protocol features easy operation, with no need for external redox reagent, and a broad functional group compatibility.

Funder

National Natural Science Foundation of China

Jiangsu National Synergistic Innovation Center for Advanced Materials

Priority Academic Program Development of Jiangsu Higher Education Institutions

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/QO/D1QO01015H

Reference51 articles.

1. An overview of N-heterocyclic carbenes