Assessment of intercalative interaction of the benzophenanthridine plant alkaloid nitidine with higher-ordered forms of RNA: spectroscopic evaluation
Author:
Affiliation:
1. Department of Chemistry
2. Jadavpur University
3. Raja S. C. Mullick Road
4. Kolkata 700 032
5. India
Abstract
Spectrophotometric, spectropolarimetric, viscometric and spectrofluorimetric analysis of the binding of the alkaloid nitidine to double- and triple-helical forms of RNA have served to highlight the ability of this drug to produce changes in the structure of RNA.
Funder
University Grants Commission
Publisher
Royal Society of Chemistry (RSC)
Subject
Materials Chemistry,General Chemistry,Catalysis
Link
http://pubs.rsc.org/en/content/articlepdf/2018/NJ/C8NJ03705A
Reference42 articles.
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3. Stability of triple helices containing RNA and DNA strands: experimental and molecular modeling studies
4. DNA H form requires a homopurine–homopyrimidine mirror repeat
5. Drug binding to higher ordered DNA structures: netropsin complexation with a nucleic acid triple helix.
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3. Molecular insight into the binding aspects of benzo[c]phenanthridine alkaloid nitidine with bovine hemoglobin: A biophysical exploration;Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy;2019-12
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