Asymmetric hydroalkylation of alkynes and allenes with imidazolidinone derivatives: α-alkenylation of α-amino acids-Reference-Cited by-同舟云学术

Asymmetric hydroalkylation of alkynes and allenes with imidazolidinone derivatives: α-alkenylation of α-amino acids

Published:2021 Issue: Volume: Page:
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Panahi Farhad¹²³⁴,Khosravi Hormoz¹²³⁴^ORCID,Bauer Felix¹²³⁴,Breit Bernhard¹²³⁴^ORCID

Affiliation:

1. Institut für Organische Chemie

2. Albert-Ludwigs-Universität Freiburg

3. 79104 Freiburg im Breisgau

4. Germany

Abstract

Enantio-, diastereoselective, geometry-selective addition of imidazolidinone derivatives to alkynes and allenes in the presence of LiHMDS in order to obtain quaternary α-alkenyl substituted amino acids in high isolated yields.

Funder

Alexander von Humboldt-Stiftung

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/SC/D1SC00240F

Reference27 articles.

1. Asymmetric Synthesis of Quaternary α-Amino Acids and Their Phosphonate Analogues

2. Advances in the synthesis of α-quaternary α-ethynyl α-amino acids

3. Phase-Transfer-Catalyzed Asymmetric SNAr Reaction of α-Amino Acid Derivatives with Arene Chromium Complexes

4. Asymmetric α-arylation of amino acids

5. Geometry-Retentive C-Alkenylation of Lithiated α-Aminonitriles: Quaternary α-Alkenyl Amino Acids and Hydantoins

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