Imaging-guided bioreactor for de-epithelialization and long-term cultivation of <i>ex vivo</i> rat trachea-Reference-Cited by-同舟云学术

Imaging-guided bioreactor for de-epithelialization and long-term cultivation of ex vivo rat trachea

Published:2022 Issue:5 Volume:22 Page:1018-1031
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Mir Seyed Mohammad¹,Chen Jiawen¹,Pinezich Meghan R.²,O'Neill John D.³,Huang Sarah X. L.⁴,Vunjak-Novakovic Gordana²^ORCID,Kim Jinho¹^ORCID

Affiliation:

1. Department of Biomedical Engineering, Stevens Institute of Technology, Hoboken, NJ, USA

2. Department of Biomedical Engineering, Columbia University, New York, NY, USA

3. Department of Cell Biology, State University of New York Downstate Medical Center, Brooklyn, NY, USA

4. Center for Stem Cell and Regenerative Medicine, University of Texas Health Science Center, Houston, TX, USA

Abstract

An imaging-enabled rat trachea bioreactor is developed that can permit controllable in vitro epithelium replacement, in situ cell monitoring, and long-term tissue scaffold cultivation.

Funder

New Jersey Health Foundation

National Institutes of Health

American Thoracic Society

Division of Civil, Mechanical and Manufacturing Innovation

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2022/LC/D1LC01105G

Reference76 articles.

1. Optimization of Normal Human Bronchial Epithelial (NHBE) Cell 3D Cultures for in vitro Lung Model Studies

2. New Rules for Club Development: New Insights into Human Small Airway Epithelial Club Cell Ontogeny and Function

3. Airway Epithelial Cells: Current Concepts and Challenges

4. Mucociliary clearance in the airways.

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