Electrochemically enhanced deoxygenative cross-coupling of aryl ketones with heteroarenes through in situ generated benzyl carbocations

Author:

Zhang Yiyi12,Hou Jianxin2,Yang Hui2,Wang Shengdong1,Yuan Kedong1ORCID

Affiliation:

1. Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology, the NMPA and State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences and the Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou 511436, China

2. Tianjin Key Laboratory of Advanced Functional Porous Materials, Institute for New Energy Materials and Low-Carbon Technologies, School of Materials Science and Engineering, Tianjin University of Technology, Tianjin, 300384, P.R. China

Abstract

Triflic acids/silanes as cooperative reductants enable Csp2–Csp3 bond formation from aryl ketones and heteroarenes in one pot.

Funder

Natural Science Foundation of Tianjin City

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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