Unexpected DNA binding properties with correlated downstream biological applications in mono vs. bis-1,8-naphthalimide Ru(ii)-polypyridyl conjugates

Author:

Ryan Gary J.1234,Poynton Fergus E.1234,Elmes Robert B. P.1234,Erby Marialuisa56234,Williams D. Clive56234,Quinn Susan J.7894,Gunnlaugsson Thorfinnur1234

Affiliation:

1. School of Chemistry and Trinity Biomedical Sciences Institute (TBSI)

2. Trinity College Dublin

3. Dublin 2

4. Ireland

5. School of Biochemistry and Immunology

6. and Trinity Biomedical Sciences Institute (TBSI)

7. School of Chemistry and Chemical Biology

8. University College Dublin

9. Dublin 4

Abstract

The development of two 1,8-napthalimide-conjugated Ru(ii)-polypyridyl complexes which exhibit different DNA binding and photocleavage behavior is presented.

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

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