Transcriptome-guided discovery and functional characterization of two UDP-sugar 4-epimerase families involved in the biosynthesis of anti-tumor polysaccharides in Ornithogalum caudatum-Reference-Cited by-同舟云学术

Transcriptome-guided discovery and functional characterization of two UDP-sugar 4-epimerase families involved in the biosynthesis of anti-tumor polysaccharides in Ornithogalum caudatum

Published:2016 Issue:44 Volume:6 Page:37370-37384
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Yin Sen¹²³⁴,Kong Jian-Qiang¹²³⁴

Affiliation:

1. Institute of Materia Medica

2. Chinese Academy of Medical Sciences & Peking Union Medical College (State Key Laboratory of Bioactive Substance and Function of Natural Medicines & Ministry of Health Key Laboratory of Biosynthesis of Natural Products)

3. Beijing

4. China

Abstract

A transcriptome-guided discovery and functional identification of UGE and UXE families were presented. Importantly, OcUGE1/2 and OcUXE1 were preliminarily revealed to be responsible for the biosynthesis of anticancer polysaccharides inO. caudatum.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA03817D

Reference54 articles.

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4. Nucleotide sugar interconversions and cell wall biosynthesis: how to bring the inside to the outside

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