Biocompatibility studies on cerium oxide nanoparticles – combined study for local effects, systemic toxicity and genotoxicity via implantation route

Author:

Kalyanaraman V.123,Naveen Sangeetha Vasudevaraj123,Mohana N.123,Balaje R. M.123,Navaneethakrishnan K. R.123,Brabu B.45678ORCID,Murugan S. S.123910,Kumaravel T. S.123910ORCID

Affiliation:

1. GLR Laboratories Private Limited

2. Chennai 600068

3. India

4. Nanoregulatory Platform

5. Pharma Chemistry

6. Drug Discovery and Development

7. Instituto Italiano di Tecnologia (IIT)

8. Genova 16163

9. GLR Laboratories (Europe) Private Limited

10. Sharnbrook MK44 1LZ

Abstract

Cerium oxide nanoparticles showed negligible local effects, low systemic toxicity and genotoxicity via implantation route.

Publisher

Oxford University Press (OUP)

Subject

Health, Toxicology and Mutagenesis,Toxicology

Reference34 articles.

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3. Use of Silver Nanoparticles Reduces Internal Contamination of External Hexagon Implants by Candida albicans

4. K. Reinhardt and H.Winkler , Cerium mischmetal, cerium alloys, and cerium compounds , in: Ullmann's encyclopedia of industrial chemistry , Wiley-VCH , Weinheim, Germany , 2002 , vol. 7 , pp. 285–300

5. J. B. Hedrick , Rare earths. Minerals yearbook. Vol. I. Metals and minerals. U.S. Geological Survey , U.S. Department of the Interior , Reston, VA , 2004

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