Digital image analysis for biothreat detection <i>via</i> rapid centrifugal microfluidic orthogonal flow immunocapture-Reference-Cited by-同舟云学术

Digital image analysis for biothreat detection via rapid centrifugal microfluidic orthogonal flow immunocapture

Published:2023 Issue:15 Volume:15 Page:1870-1880
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Woolf M. Shane¹^ORCID,Dignan Leah M.¹,Karas Scott M.¹,Lewis Hannah M.¹,Kim Sabrina N.¹,Geise Geoffrey M.²^ORCID,DeMers Haley L.³,Hau Derrick³,Gates-Hollingsworth Marcellene A.³,AuCoin David P.³,Landers James P.¹⁴⁵

Affiliation:

1. Department of Chemistry, University of Virginia, USA

2. Department of Chemical Engineering, University of Virginia, USA

3. Department of Microbiology and Immunology, University of Nevada, Reno, USA

4. Department of Mechanical Engineering, University of Virginia, USA

5. Department of Pathology, University of Virginia, USA

Abstract

We report centrifugally-driven, orthogonal flow immunocapture (cOFI) of Zaire Ebola virus-like particles with an accompanying rich, colorimetric image analysis approach that does not require commercial ‘strip readers’ or custom analysis algorithms.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/AY/D3AY00073G

Reference55 articles.

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5. Lateral flow assays

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