Enantioselective [3 + 2] annulation of 4-isothiocyanato pyrazolones and alkynyl ketones under organocatalysis
Author:
Affiliation:
1. State Key Laboratory of Fine Chemicals
2. Department of Pharmaceutical Sciences
3. School of Chemical Engineering
4. Dalian University of Technology
5. Dalian 116024
Abstract
An asymmetric [3 + 2] annulation reaction of 4-isothiocyanato pyrazolones with alkynyl ketones is developed, providing expeditious access to spiro[pyrroline–pyrazolones].
Funder
Fundamental Research Funds for the Central Universities
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2021/OB/D0OB02423F
Reference52 articles.
1. The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2. Ligand-Based Virtual Screening, Parallel Solution-Phase and Microwave-Assisted Synthesis as Tools to Identify and Synthesize New Inhibitors ofMycobacterium tuberculosis
3. Chapter 2 Pyrazol-3-ones. Part IV: Synthesis and Applications
4. Development of the next generation of HIV-1 integrase inhibitors: Pyrazolone as a novel inhibitor scaffold
5. From 2000 to Mid-2010: A Fruitful Decade for the Synthesis of Pyrazoles
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