Integrated DNA and RNA extraction and purification on an automated microfluidic cassette from bacterial and viral pathogens causing community-acquired lower respiratory tract infections

Author:

Van Heirstraeten Liesbet1234,Spang Peter56,Schwind Carmen56,Drese Klaus S.56,Ritzi-Lehnert Marion56,Nieto Benjamin78,Camps Marta78,Landgraf Bryan78,Guasch Francesc78,Corbera Antoni Homs9101112,Samitier Josep9101112,Goossens Herman1234,Malhotra-Kumar Surbhi1234,Roeser Tina56

Affiliation:

1. Department of Medical Microbiology

2. Vaccine & Infectious Disease Institute (VAXINFECTIO)

3. Universiteit Antwerpen

4. Antwerp, Belgium

5. Institut für Mikrotechnik Mainz GmbH (IMM)

6. 55129 Mainz, Germany

7. Biokit

8. , Spain

9. Institut de Bioenginyeria de Catalunya (IBEC)

10. CIBER-BBN

11. Universitat de Barcelona (UB)

12. Barcelona, Spain

Abstract

Fully automated LOC can reproduce and outperform benchtop NA-sample preparation starting with swab samples.

Funder

European Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

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