Synthesis and biological evaluation of thiolate gold(i) complexes as thioredoxin reductase (TrxR) and glutathione reductase (GR) inhibitors-Reference-Cited by-同舟云学术

Synthesis and biological evaluation of thiolate gold(i) complexes as thioredoxin reductase (TrxR) and glutathione reductase (GR) inhibitors

Published:2019 Issue:33 Volume:43 Page:13173-13182
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Fereidoonnezhad Masood¹²³⁴⁵^ORCID,Ahmadi Mirsadeghi Hasti⁶⁷⁸⁵,Abedanzadeh Sedigheh⁹¹⁰¹¹⁵,Yazdani Alireza¹²³⁴⁵,Alamdarlou Arsalan¹²³⁴⁵,Babaghasabha Mojgan⁶⁷⁸⁵,Almansaf Zainab¹²¹³¹⁴¹⁵,Faghih Zeinab¹⁶¹⁷¹⁸⁵^ORCID,McConnell Zachary¹²¹³¹⁴¹⁵,Shahsavari Hamid R.⁶⁷⁸⁵¹²^ORCID,Beyzavi M. Hassan¹²¹³¹⁴¹⁵^ORCID

Affiliation:

1. Toxicology Research Center; Department of Medicinal Chemistry

2. School of Pharmacy

3. Ahvaz Jundishapur University of Medical Sciences

4. Ahvaz

5. Iran

6. Department of Chemistry

7. Institute for Advanced Studies in Basic Sciences (IASBS)

8. Zanjan 45137-66731

9. Institute of Biochemistry and Biophysics (IBB)

10. University of Tehran

11. Tehran

12. Department of Chemistry and Biochemistry

13. University of Arkansas

14. Fayetteville

15. USA

16. Pharmaceutical Sciences Research Center

17. Shiraz University of Medical Sciences

18. Shiraz

Abstract

Au(i) complexes with PPh₂py and thiolate ligands are prepared. The complexes are shown considerable cytotoxic activities and those efficiently inhibit the TrxRs and GR.

Funder

Iran National Science Foundation

Ahvaz Jundishapur University of Medical Sciences

University of Arkansas

Institute for Advanced Studies in Basic Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2019/NJ/C9NJ02502B

Reference48 articles.