Pterostilbene alleviates abdominal aortic aneurysm <i>via</i> inhibiting macrophage pyroptosis by activating the miR-146a-5p/TRAF6 axis-Reference-Cited by-同舟云学术

Pterostilbene alleviates abdominal aortic aneurysm via inhibiting macrophage pyroptosis by activating the miR-146a-5p/TRAF6 axis

Published:2024 Issue:1 Volume:15 Page:139-157
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Cai Huoying¹²,Huang Lin¹²,Wang Mingshan¹²,Liu Ruiming³,Qiu Jiacong⁴,Qin Yuansen¹²,Yao Xi⁵^ORCID,Wang Shenming¹²,Yao Chen¹²,Hu Zuojun¹²,Zhou Yu¹²^ORCID

Affiliation:

1. Department of Vascular Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China

2. National-Guangdong Joint Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases, Guangzhou, Guangdong, China

3. Laboratory of General Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China

4. Department of Vascular Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang University, Nanchang, Jiangxi 330006, China

5. Department of Biomedical Sciences, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong

Abstract

Our findings provide evidence that macrophage pyroptosis contributes to the development of AAA and that the activation of the miR-146a/TRAF6 axis by pterostilbene protects against macrophage pyroptosis and AAA formation.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2024/FO/D3FO01235B

Reference66 articles.

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