Microwave-assisted synthesis, molecular docking and antiproliferative activity of (3/5-aryl-1,2,4-oxadiazole-5/3-yl)(3,4,5-trimethoxyphenyl)methanone oxime derivatives-Reference-Cited by-同舟云学术

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Microwave-assisted synthesis, molecular docking and antiproliferative activity of (3/5-aryl-1,2,4-oxadiazole-5/3-yl)(3,4,5-trimethoxyphenyl)methanone oxime derivatives

Published:2015 Issue:8 Volume:6 Page:1484-1493
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Guan Qi¹²³⁴⁵,Feng Dongjie¹²³⁴⁵,Bai Zhaoshi⁶³⁴⁵,Cui Yuanhang¹²³⁴⁵,Zuo Daiying⁶³⁴⁵,Zhai Min'an¹²³⁴⁵,Jiang Xuewei⁶³⁴⁵,Zhou Wenbo¹²³⁴⁵,Bao Kai¹²³⁴⁵,Wu Yingliang⁶³⁴⁵,Zhang Weige¹²³⁴⁵

Affiliation:

1. Key Laboratory of Structure-Based Drug Design and Discovery

2. Ministry of Education

3. Shenyang Pharmaceutical University

4. Shenyang 110016

5. China

6. Department of Pharmacology

Abstract

A microwave-assisted synthesis method of building a 1,2,4-oxadiazole skeleton was developed.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/MD/C5MD00150A

Reference26 articles.

1. An Overview of Tubulin Inhibitors That Interact with the Colchicine Binding Site

2. Recent developments in tubulin polymerization inhibitors: An overview

3. Discovery of 4-Substituted Methoxybenzoyl-aryl-thiazole as Novel Anticancer Agents: Synthesis, Biological Evaluation, and Structure−Activity Relationships

4. Discovery of Novel 2-Aryl-4-benzoyl-imidazoles Targeting the Colchicines Binding Site in Tubulin As Potential Anticancer Agents

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1. Design, synthesis and biological evaluation of 1-Aryl-5-(4-arylpiperazine-1-carbonyl)-1H-tetrazols as novel microtubule destabilizers;Journal of Enzyme Inhibition and Medicinal Chemistry;2021-01-01

2. Iron Nitrate-Mediated Selective Synthesis of 3-Acyl-1,2,4-oxadiazoles from Alkynes and Nitriles: The Dual Roles of Iron Nitrate;The Journal of Organic Chemistry;2020-01-29

3. Conformation impacts on the bioactivities of SMART analogues;European Journal of Medicinal Chemistry;2018-10

4. Synthesis and biological evaluation of (1-aryl-1H-pyrazol-4-yl) (3,4,5-trimethoxyphenyl)methanone derivatives as tubulin inhibitors;European Journal of Medicinal Chemistry;2018-08

5. Metal-Involving Synthesis and Reactions of Oximes;Chemical Reviews;2017-10-09

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