Squaramide-catalysed asymmetric Michael addition/cyclization cascade reaction of 4-arylmethylidene-2,3-dioxopyrrolidines with 2-isothiocyanato-1-indanones-Reference-Cited by-同舟云学术

Squaramide-catalysed asymmetric Michael addition/cyclization cascade reaction of 4-arylmethylidene-2,3-dioxopyrrolidines with 2-isothiocyanato-1-indanones

Published:2021 Issue:33 Volume:19 Page:7181-7185
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Hou Xi-Qiang¹,Wen Jiang-Bo¹,Yan Li²,Du Da-Ming¹^ORCID

Affiliation:

1. School of Chemistry and Chemical Engineering Beijing Institute of Technology, 5 South Zhongguancun Street, Beijing 100081, P. R. China

2. Analytical and Testing Center, Beijing Institute of Technology, Liangxiang Campus, Liangxiang East Road, Beijing 102488, People's Republic of China

Abstract

An efficient squaramide-catalysed asymmetric Michael/cyclization cascade reaction of 4-arylidene-2,3-dioxopyrrolidines with 2-isothiocyanato-1-indanones afforded indanone-derived spiropyrrolidones in excellent yields with high stereoselectivities.

Funder

National Natural Science Foundation of China

Beijing Institute of Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB01223A

Reference26 articles.

1. Enantioselective methodologies for the synthesis of spiro compounds

2. Total syntheses of natural products containing spirocarbocycles