<i>In vitro</i> vascularized liver tumor model based on a microfluidic inverse opal scaffold for immune cell recruitment investigation-Reference-Cited by-同舟云学术

In vitro vascularized liver tumor model based on a microfluidic inverse opal scaffold for immune cell recruitment investigation

Published:2024 Issue:14 Volume:24 Page:3470-3479
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Xu Pingwei¹,Chi Junjie¹^ORCID,Wang Xiaochen¹²³,Zhu Meng⁴,Chen Kai⁵,Fan Qihui³^ORCID,Ye Fangfu¹²³^ORCID,Shao Changmin¹²^ORCID

Affiliation:

1. Joint Centre of Translational Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325035, China

2. Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou 325001, China

3. Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100190, China

4. The First Clinical Medical College, Wenzhou Medical University, Wenzhou 325035, China

5. Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325035, China

Abstract

A well-defined inverse opal scaffold generated by droplet microfluidics is proposed for the construction of a vascularized liver tumor model, offering insights into immune cells' recruitment.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China

Natural Science Foundation of Zhejiang Province

Primary Research and Development Plan of Zhejiang Province

Key Research and Development Program of Zhejiang Province

Youth Innovation Promotion Association of the Chinese Academy of Sciences

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/LC/D4LC00341A

Reference46 articles.

1. Clinical characteristics, surveillance, treatment allocation, and outcomes of non-alcoholic fatty liver disease-related hepatocellular carcinoma: a systematic review and meta-analysis

2. Circulating biomarkers in the diagnosis and management of hepatocellular carcinoma

3. The liver cancer immune microenvironment: Therapeutic implications for hepatocellular carcinoma

4. Neutrophils as potential therapeutic targets in hepatocellular carcinoma

5. Hepatocellular Carcinoma Immunotherapy