A high-performance liquid chromatography method validation and a Box–Behnken experimental design for the extraction optimization of quercitrin from Nectandra reticulata

Author:

Pulido Teuta Juanita1,Narváez-Cuenca Carlos-Eduardo2ORCID,Ávila Murillo Mónica1

Affiliation:

1. Universidad Nacional de Colombia, Sede Bogotá, Facultad de Ciencias, Departamento de Química, Quipronab, Carrera 30 No. 45-03, Bogotá, Colombia

2. Universidad Nacional de Colombia, Sede Bogotá, Facultad de Ciencias, Departamento de Química, Food Chemistry Research Group, Carrera 30 No. 45-03, Bogotá, Colombia

Abstract

The lower the content of ethanol in the extraction mixture and the higher the temperature, the higher the extraction of quercitrin.

Funder

Ministerio de Ciencia, Tecnología e Innovación

Publisher

Royal Society of Chemistry (RSC)

Reference44 articles.

1. A. M.Bustos Rangel , Búsqueda de agonistas LXR en plantas colombianas con potencial terapéutico para la enfermedad de Alzheimer , 2021 , https://repositorio.unal.edu.co/handle/unal/80277 , accessed March 12, 2022

2. J.Pulido-Teuta , F.Lopez-Vallejo , A.Sandoval-Hernandez , C.-E.Narváez-Cuenca and M.Avila-Murillo , Bioactive glycosylated flavonoids with LXRs agonist activity in an ethanolic extract from Nectandra reticulate , submitted to

3. The Flavonol Quercitrin Hinders GSK3 Activity and Potentiates the Wnt/β-Catenin Signaling Pathway

4. Comparable Attenuation of Aβ25–35-Induced Neurotoxicity by Quercitrin and 17β-Estradiol in Cultured Rat Hippocampal Neurons

5. Bio-guided isolation of anti-Alzheimer’s compounds from Phyllanthus niruri and role of niruriflavone in the reversal of aluminum chloride-induced neurobehavioral and biochemical changes in an animal model

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