A lysosome-targeted probe for the real-time detection of hypobromous acid in living human cancer cells-Reference-Cited by-同舟云学术

A lysosome-targeted probe for the real-time detection of hypobromous acid in living human cancer cells

Published:2021 Issue:8 Volume:146 Page:2484-2489
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Wang Yali¹²³⁴⁵,Zhang Yuan¹²³⁴⁵,Yang Lijun⁶⁷⁸⁵,Wu Huiyuan¹²³⁴⁵,Finney Nathaniel¹²³⁴⁵^ORCID

Affiliation:

1. School of Pharmaceutical Sciences and Technology

2. Health Sciences Platform

3. Tianjin University

4. Tianjin 300072

5. China

6. College of Materials Science and Engineering

7. Qingdao University of Science and Technology

8. Qingdao

Abstract

We describe here LysOBr, one of the most sensitive HOBr-responsive fluorescent probes known. Imaging in live Hela cells shows that it localizes in the lysosome, and provides ∼50-fold fluorescence enhancement upon reaction with HOBr.

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

China Postdoctoral Science Foundation

Tianjin University

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/AN/D1AN00147G

Reference49 articles.

1. Kinetic Analysis of the Reactions of Hypobromous Acid with Protein Components: Implications for Cellular Damage and Use of 3-Bromotyrosine as a Marker of Oxidative Stress

2. Science and technology for water purification in the coming decades

3. Studies on the chlorinating activity of myeloperoxidase.

4. Myeloperoxidase: a key regulator of neutrophil oxidant production

5. Eosinophils Preferentially Use Bromide to Generate Halogenating Agents

Cited by 10 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Sulfur-based fluorescent probes for biological analysis: A review;Talanta;2024-11

2. Development of a highly specific NIR fluorescent probe for imaging of mitochondrial HOBr fluctuations;Dyes and Pigments;2024-07

3. α-Aminophosphonates Containing Sterically Hindered Phenolic and N-Heterocyclic Fragments as Potentional Antitumor Agents;Russian Journal of General Chemistry;2024-02

4. Fast detection of hypobromous acid in cells and the water environment using a lysosome-targeted fluorescent probe;Organic & Biomolecular Chemistry;2024

5. A ratiometric fluorescent probe for imaging the fluctuation of HOBr during endoplasmic reticulum stress;Journal of Materials Chemistry B;2024