Novel asymmetric biscarbothioamides as Alzheimer's disease associated cholinesterase inhibitors: synthesis, biological activity, and molecular docking studies-Reference-Cited by-同舟云学术

Novel asymmetric biscarbothioamides as Alzheimer's disease associated cholinesterase inhibitors: synthesis, biological activity, and molecular docking studies

Published:2024 Issue:24 Volume:48 Page:10979-10989
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Muğlu Halit¹,Yakan Hasan²^ORCID,Erdoğan Musa³^ORCID,Topal Fevzi⁴^ORCID,Topal Meryem⁵,Türkeş Cüneyt⁶,Beydemir Şükrü⁷⁸

Affiliation:

1. Department of Chemistry, Faculty of Sciences, Kastamonu University, Kastamonu 37200, Turkey

2. Department of Chemistry Education, Faculty of Education, Ondokuz Mayis University, Samsun 55200, Turkey

3. Department of Food Engineering, Faculty of Engineering and Architecture, Kafkas University, Kars 36100, Turkey

4. Department of Chemical and Chemical Processing Technologies, Laboratory Technology, Gümüşhane University, Gümüşhane 29100, Turkey

5. Vocational School of Health Services, Gümüşhane University, Gümüşhane 29100, Turkey

6. Department of Biochemistry, Faculty of Pharmacy, Erzincan Binali Yıldırım University, Erzincan 24002, Turkey

7. Department of Biochemistry, Faculty of Pharmacy, Anadolu University, Eskişehir 26470, Turkey

8. Bilecik Şeyh Edebali University, Bilecik 11230, Turkey

Abstract

Investigating innovative frameworks for addressing Alzheimer's disease is a challenging goal. In this specific scenario, a selection of asymmetric biscarbothioamide derivatives (3a–l) with different substitutions has been carefully formulated and successfully synthesized.

Funder

Anadolu Üniversitesi

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/NJ/D4NJ01462F

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