Synthesis and preliminary anti-inflammatory and anti-bacterial evaluation of some diflunisal aza-analogs-Reference-Cited by-同舟云学术

Synthesis and preliminary anti-inflammatory and anti-bacterial evaluation of some diflunisal aza-analogs

Published:2018 Issue:6 Volume:9 Page:1017-1032
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Carta Davide¹²³⁴⁵,Brun Paola⁶³⁴⁵^ORCID,Dal Pra Matteo¹²³⁴⁵,Bernabè Giulia⁶³⁴⁵,Castagliuolo Ignazio⁶³⁴⁵,Ferlin Maria Grazia¹²³⁴⁵^ORCID

Affiliation:

1. Department of Pharmaceutical and

2. Pharmacological Sciences

3. University of Padova

4. 35131 Padova

5. Italy

6. Department of Molecular Medicine

Abstract

The new diflunisal aza-analogs multi-target approach is remarkable in the treatment of infections induced by multi-drug resistant bacteria. Diflunisal aza-analogs preserved the anti-inflammatory activity and significantly potentiated the antimicrobial activity of antibiotics.

Funder

Università degli Studi di Padova

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/MD/C8MD00139A

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